In this issue of JAMA Cardiology, Whelton et al1 report an analysis of data from the Multi-Ethnic Study of Atherosclerosis Study that provides insight into the association between blood pressure (BP) and incident atherosclerotic cardiovascular disease (ASCVD), as well as the prevalence of coronary artery calcium. The key finding in the analysis is that, in persons free of hypertension as currently defined, free of known ASCVD, and free of other risk factors as currently defined, the risk imposed by a BP level below the currently defined hypertensive level is continuous beginning at a systolic BP level as low as 90 mm Hg.
Jones DW. What Is a Normal Blood Pressure? JAMA Cardiol. 2020;5(9):1018–1019. doi:10.1001/jamacardio.2020.1742
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