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June 24, 2020

The Way Forward in Congenital Heart Disease Research

Author Affiliations
  • 1Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland
  • 2Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, Maryland
JAMA Cardiol. Published online June 24, 2020. doi:10.1001/jamacardio.2020.2034

The time has come for the congenital heart disease (CHD) community to identify the ways our approach to clinical trials will need to change if we want to produce the data necessary to help the aging CHD population. Although there are a few large, well-conceived clinical trials in CHD that have been conducted in the model of clinical trials which have led to dramatic progress in adult cardiology, we believe trials in patients with CHD may require a nontraditional approach to achieve success.

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