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Cardiovascular Images
August 19, 2020

A Man in His 30s With a New Continuous Murmur and Fever

Author Affiliations
  • 1Harvard Medical School, Boston, Massachusetts
  • 2Division of Cardiology, Department of Medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston, Massachusetts
JAMA Cardiol. 2020;5(8):e203255. doi:10.1001/jamacardio.2020.3255

What is the cause of the continuous murmur in this patient with a fever? Fever and a new heart murmur in a young patient appropriately raise a concern of infective endocarditis. Initial diagnostic workup includes blood cultures and transthoracic echocardiography,1 which may show a regurgitant jet across an affected heart valve. However, jet appearance and the association with patient history and physical examination findings may suggest alternative diagnoses.

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