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Comment & Response
September 2, 2020

Residual Challenges in Radial Approach for Percutaneous Coronary Interventions—Reply

Author Affiliations
  • 1Division of Cardiology, Department of Medicine, University of Ottawa Heart Institute, Ottawa, Ontario, Canada
JAMA Cardiol. 2020;5(12):1451-1452. doi:10.1001/jamacardio.2020.3730

In Reply We thank Agostoni and colleagues for their interest in the Safety and Efficacy of Femoral Access vs Radial Access in ST-Elevation Myocardial Infarction (SAFARI-STEMI) trial.1 They suggest that bleeding could be significantly reduced by eliminating crossovers from radial access (RA) to femoral access (FA). In the SAFARI-STEMI trial, crossover from RA to FA occurred in 92 of 1236 patients (8.1%). This crossover rate is similar to the rates reported in other randomized trials, ie, in the Radial vs Femoral Access for Coronary Intervention (RIVAL) trial,2 it was 7.6%, and in the Radial Versus Femoral Randomized Investigation in ST-Elevation Acute Coronary Syndrome (RIFLE-STEACS) trial,3 it was 9.6%.

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