The link between osteoporosis and cardiovascular diseases has been extensively reported, and previous studies show an inverse association between trabecular bone volumetric bone mineral density (Tb.vBMD) in the spine and coronary artery calcification score (CACS).1,2 However, the association between cortical vBMD (Ct.vBMD) in the long bones and CACS may differ from the association for Tb.vBMD because the 2 bone compartments are largely differentially regulated.3
Funck-Brentano T, Grahnemo L, Hjelmgren O, Brandberg J, Bergström G, Ohlsson C. Associations of Trabecular and Cortical Volumetric Bone Mineral Density With Coronary Artery Calcification Score: The Swedish Cardiopulmonary Bioimage Study Pilot Study. JAMA Cardiol. Published online October 14, 2020. doi:10.1001/jamacardio.2020.4880
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