[Skip to Content]
[Skip to Content Landing]
Views 516
Citations 0
Research Letter
October 14, 2020

Associations of Trabecular and Cortical Volumetric Bone Mineral Density With Coronary Artery Calcification Score: The Swedish Cardiopulmonary Bioimage Study Pilot Study

Author Affiliations
  • 1Center for Bone and Arthritis Research, Institute of Medicine, Department of Internal Medicine and Clinical Nutrition, The Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden
  • 2Lariboisière Hospital, Department of Rheumatology, Université de Paris, Paris, France
  • 3Department of Clinical Physiology, Sahlgrenska University Hospital, Gothenburg, Sweden
  • 4Department of Molecular and Clinical Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden
  • 5Institute of Clinical Sciences, Department of Radiology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden
  • 6Department of Radiology, Sahlgrenska University Hospital, Gothenburg, Sweden
  • 7Region Västra Götaland, Department of Drug Treatment, Sahlgrenska University Hospital, Gothenburg, Sweden
JAMA Cardiol. Published online October 14, 2020. doi:10.1001/jamacardio.2020.4880

The link between osteoporosis and cardiovascular diseases has been extensively reported, and previous studies show an inverse association between trabecular bone volumetric bone mineral density (Tb.vBMD) in the spine and coronary artery calcification score (CACS).1,2 However, the association between cortical vBMD (Ct.vBMD) in the long bones and CACS may differ from the association for Tb.vBMD because the 2 bone compartments are largely differentially regulated.3

×