To the Editor We read with great interest the robust study by Adusumalli et al,1 which compared the effect of passive with active prompts in an electronic health record to improve optimal statin dosing. Even among patients with atherosclerotic cardiovascular disease (ASCVD), there was negligible impact. Inertia for prescribing and titrating statins adversely affects the quality of care. This is remarkable, given that statins reduce risk for myocardial infarction, ischemic stroke, revascularization, and death and that higher doses of statins reduce risk more than lower doses.2 The role of low-density lipoprotein cholesterol in atherogenesis is one of the most established cause-and-effect relationships in all of medicine. The optimal dose and potency of statin therapy based on risk is highly defined by guidelines around the world.
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Mark L, Reiber I, Toth PP. Statin Prescribing and Dosing—Failure Has Become an Option. JAMA Cardiol. 2021;6(7):854–855. doi:10.1001/jamacardio.2021.0832
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