To the Editor We appreciate the work of Berman and colleagues,1 who investigated the association between socioeconomic disadvantage and mortality after a myocardial infarction (MI). The authors found that among people who had an MI before age 50 years, patients who lived in the most disadvantaged neighborhoods had a higher risk of all-cause and cardiovascular mortality. These findings suggest that addressing socioeconomic disadvantage among working-age adults may be key to reducing years of life lost to cardiovascular diseases. This is also highlighted in the Invited Commentary by Havranek.2