Achieving and maintaining good neurologic function and health-related quality of life after discharge are key goals for those who are affected by or care for those with out-of-hospital cardiac arrest (OHCA). Inaccurate early assessment of prognosis and consequent withdrawal of life-sustaining treatment can limit patients’ opportunities to achieve these goals. As emergency department and intensive care practitioners, we are aware that caregivers sometimes do not perform key diagnostic procedures (eg, emergency coronary angiography) and sometimes initiate early withdrawal of life-sustaining treatment in part out of their own or family members’ concern that a resuscitated patient will die or have poor functional outcome regardless of whether additional tests or treatments are used.