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March 2021 - April 2016

Decade

Year

Issue

April 2021, Vol 6, No. 4, Pages 373-485

Original Investigation

Assessing the Role of Rare Genetic Variation in Patients With Heart Failure

Abstract Full Text
has active quiz
JAMA Cardiol. 2021;6(4):379-386. doi:10.1001/jamacardio.2020.6500

This gene-based collapsing analysis assesses the contribution of rare variants to all-cause heart failure with and without reduced left ventricular ejection fraction.

Association of Genetic West African Ancestry, Blood Pressure Response to Therapy, and Cardiovascular Risk Among Self-reported Black Individuals in the Systolic Blood Pressure Reduction Intervention Trial (SPRINT)

Abstract Full Text
JAMA Cardiol. 2021;6(4):388-398. doi:10.1001/jamacardio.2020.6566

This post hoc analysis of data from the Systolic Blood Pressure Intervention Trial determines the association between the proportion of West African ancestry with response to antihypertensive medication, blood pressure control, kidney function, and risk of adverse cardiovascular events among self-identified Black individuals.

Differences in Long-term Outcomes After Coronary Artery Bypass Grafting Using Single vs Multiple Arterial Grafts and the Association With Sex

Abstract Full Text
has audio
JAMA Cardiol. 2021;6(4):401-409. doi:10.1001/jamacardio.2020.6585

This cohort study compares the outcomes of the use of multiple arterial grafts vs a single arterial graft during coronary artery bypass grafting for women and men.

Assessing the Risks of Bleeding vs Thrombotic Events in Patients at High Bleeding Risk After Coronary Stent Implantation: The ARC–High Bleeding Risk Trade-off Model

Abstract Full Text
JAMA Cardiol. 2021;6(4):410-419. doi:10.1001/jamacardio.2020.6814

This prognostic study develops and validates models to predict the risks of major bleeding (Bleeding Academic Research Consortium types 3-5 bleeding) and myocardial infarction and/or stent thrombosis for individual patients at high bleeding risk.

Effectiveness of Systematic Echocardiographic Screening for Rheumatic Heart Disease in Nepalese Schoolchildren: A Cluster Randomized Clinical Trial

Abstract Full Text
open access has audio
JAMA Cardiol. 2021;6(4):420-426. doi:10.1001/jamacardio.2020.7050

This cluster randomized clinical trial investigates the effect of systematic echocardiographic screening in combination with secondary antibiotic prophylaxis on the prevalence of rheumatic heart disease in schoolchildren in Nepal.

Association of Effective Regurgitation Orifice Area to Left Ventricular End-Diastolic Volume Ratio With Transcatheter Mitral Valve Repair Outcomes: A Secondary Analysis of the COAPT Trial

Abstract Full Text
JAMA Cardiol. 2021;6(4):427-436. doi:10.1001/jamacardio.2020.7200

This secondary analysis of the COAPT randomized clinical trial explores the contributions of the degree of secondary mitral regurgitation using the effective regurgitation orifice area, regurgitant volume, and left ventricular end-diastolic volume index to the benefit of transcatheter mitral valve repair.

Association of Lipid, Inflammatory, and Metabolic Biomarkers With Age at Onset for Incident Coronary Heart Disease in Women

Abstract Full Text
JAMA Cardiol. 2021;6(4):437-447. doi:10.1001/jamacardio.2020.7073

This cohort study evaluates risk factors associated with incident coronary heart disease in women by age at onset.

Association of Global Longitudinal Strain With Clinical Status and Mortality in Patients With Chronic Heart Failure

Abstract Full Text
JAMA Cardiol. 2021;6(4):448-456. doi:10.1001/jamacardio.2020.7184

This cohort study examines the use of global longitudinal strain as a tool to assess cardiac function and prognostic factors in patients with heart failure.

Brief Report

Association of Damaging Variants in Genes With Increased Cancer Risk Among Patients With Congenital Heart Disease

Abstract Full Text
open access
JAMA Cardiol. 2021;6(4):457-462. doi:10.1001/jamacardio.2020.4947

This case-control study compares the frequency of damaging cancer risk gene variants in patients with congenital heart disease vs control participants and identifies associated clinical variables.

Effectiveness of Home-Based Mobile Guided Cardiac Rehabilitation as Alternative Strategy for Nonparticipation in Clinic-Based Cardiac Rehabilitation Among Elderly Patients in Europe: A Randomized Clinical Trial

Abstract Full Text
open access
JAMA Cardiol. 2021;6(4):463-468. doi:10.1001/jamacardio.2020.5218

This randomized clinical study assesses whether a 6-month mobile cardiac rehabilitation program is an effective therapy for elderly patients who decline participation in cardiac rehabilitation.

Assessment of Neutrophil Extracellular Traps in Coronary Thrombus of a Case Series of Patients With COVID-19 and Myocardial Infarction

Abstract Full Text
free access has active quiz
JAMA Cardiol. 2021;6(4):469-474. doi:10.1001/jamacardio.2020.7308

This case series study reports formation of neutrophil extracellular traps in 5 patients with coronavirus disease 2019 with ST-elevated myocardial infarction and compares findings with 50 patients who had experienced myocardial infarction before the coronavirus disease 2019 pandemic.

Research Letter

Variability in Reported Percutaneous Coronary Intervention Mortality Among Physicians Practicing at Multiple Sites in New York State

Abstract Full Text
JAMA Cardiol. 2021;6(4):477-478. doi:10.1001/jamacardio.2020.6717

This study investigates variation in site-specific risk-adjusted mortality rates of percutaneous coronary intervention for physicians practicing at multiple sites within New York State.

Editorial

Screening for Rheumatic Heart Disease—Quo Vadis?

Abstract Full Text
has audio
JAMA Cardiol. 2021;6(4):375-376. doi:10.1001/jamacardio.2020.7063

Reconciling COAPT and Mitra-FR Results Based on Mitral Regurgitation Severity and Left Ventricular Size: It’s Not So Simple

Abstract Full Text
JAMA Cardiol. 2021;6(4):376-378. doi:10.1001/jamacardio.2020.7214
Invited Commentary
JAMA Cardiology Clinical Challenge

Unusual Wide QRS Complex Rhythm in a Teenager

Abstract Full Text
has active quiz
JAMA Cardiol. 2021;6(4):475-476. doi:10.1001/jamacardio.2020.7091

A teenaged girl presented with recurrent episodes of chest and neck palpitations accompanied by headaches for 3 years, with sudden onset and offset. What would you do next?

Cardiovascular Images

Causative Mechanism of Constrictive Pericarditis Diagnosed by Fluoroscopy

Abstract Full Text
online only
JAMA Cardiol. 2021;6(4):e210616. doi:10.1001/jamacardio.2021.0616

This case report describes a patient with constrictive pericarditis after recurrent peritonitis associated with peritoneal dialysis for end-stage kidney disease.

Comment & Response

Return-to-Play Guidelines for Athletes After COVID-19 Infection

Abstract Full Text
free access
JAMA Cardiol. 2021;6(4):478-479. doi:10.1001/jamacardio.2020.5345

Return-to-Play Guidelines for Athletes After COVID-19 Infection

Abstract Full Text
free access
JAMA Cardiol. 2021;6(4):479. doi:10.1001/jamacardio.2020.5348

Return-to-Play Guidelines for Athletes After COVID-19 Infection—Reply

Abstract Full Text
free access
JAMA Cardiol. 2021;6(4):479-480. doi:10.1001/jamacardio.2020.5351

PCSK9 Inhibition—A Tale of 2 Potential Treatment Opportunities

Abstract Full Text
JAMA Cardiol. 2021;6(4):480-481. doi:10.1001/jamacardio.2020.5606

PCSK9 Inhibition—A Tale of 2 Potential Treatment Opportunities—Reply

Abstract Full Text
JAMA Cardiol. 2021;6(4):481. doi:10.1001/jamacardio.2020.5613

The 70/30 Rule Between Men and Women—Disparity or Opportunity?

Abstract Full Text
JAMA Cardiol. 2021;6(4):481-482. doi:10.1001/jamacardio.2020.6118

The 70/30 Rule Between Men and Women—Disparity or Opportunity?—Reply

Abstract Full Text
JAMA Cardiol. 2021;6(4):482-483. doi:10.1001/jamacardio.2020.6136

Consistency and Generalizability of Trials for Coronary Computed Tomography Angiography

Abstract Full Text
JAMA Cardiol. 2021;6(4):483-484. doi:10.1001/jamacardio.2020.6124

Consistency and Generalizability of Trials for Coronary Computed Tomography Angiography—Reply

Abstract Full Text
JAMA Cardiol. 2021;6(4):484. doi:10.1001/jamacardio.2020.6133
Editor's Note

Genetic Contribution to Common Heart Failure—Not So Rare?

Abstract Full Text
JAMA Cardiol. 2021;6(4):387. doi:10.1001/jamacardio.2020.6508

Reporting Genetic Markers and the Social Determinants of Health in Clinical Cardiovascular ResearchIt Is Time to Recalibrate the Use of Race

Abstract Full Text
JAMA Cardiol. 2021;6(4):400. doi:10.1001/jamacardio.2020.6576
Correction

Error in Supplement

Abstract Full Text
free access
JAMA Cardiol. 2021;6(4):485. doi:10.1001/jamacardio.2021.0091

Error in Author Name

Abstract Full Text
free access
JAMA Cardiol. 2021;6(4):485. doi:10.1001/jamacardio.2021.0109
JAMA Cardiology Masthead

JAMA Cardiology

Abstract Full Text
free access
JAMA Cardiol. 2021;6(4):373. doi:10.1001/jamacardio.2020.4546
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