This randomized clinical trial assesses the prognosis of cardiovascular and bleeding events occurring beyond 1 year after coronary stenting.
This multicenter, randomized clinical trial investigates whether ischemic postconditioning of the infarct-related artery vs conventional percutaneous coronary intervention can improve the clinical outcomes of patients with acute onset of ST-segment elevation myocardial infarction.
This multicenter study examines access to reperfusion and percutaneous coronary intervention during ST-segment elevation myocardial infarction in Indian clinics and hospitals using a hub-and-spoke model.
This nationwide cohort study examined changes in bystander defibrillation and subsequent survival among patients with out-of-hospital cardiac arrest according to public or residential location.
This population-based cohort study evaluates the presence of inflammation markers in individuals with atrial fibrillation over a 20-year follow-up.
This patient-level analysis of the ARISTOTLE randomized clinical trial assesses the cost and cost-effectiveness of apixaban therapy compared with warfarin therapy in patients with atrial fibrillation from the perspective of the US health care system.
This cohort study investigates whether HIV infection increased the risk of future heart failure with reduced ejection fraction and heart failure with preserved ejection fraction in the Veterans Aging Cohort Study.
This prespecified analysis assesses the safety and clinical efficacy of achieving a very low (<30 mg/dL) level of low-density lipoprotein cholesterol at 1 month in patients with acute coronary syndrome using data from the Improved Reduction of Outcomes: Vytorin Efficacy International Trial.
This study of pooled data from patients in 4 randomized clinical trials characterizes variability in proprotein convertase subtilisin kexin type 9 (PCSK9) levels and determines whether the reduction in low-density lipoprotein cholesterol level achieved with evolocumab differs based on PCSK9 levels.
This cohort study identifies patient, clinician, and hospital characteristics associated with cardiac resynchronization therapy defibrillator use and determine the extent of hospital-level variation in this use among guideline-eligible patients undergoing implantable cardioverter defibrillator placement.
This study tests the hypothesis that cardiovascular magnetic resonance–derived left ventricular ejection fraction and volumes would provide improved risk stratification in patients undergoing coronary artery bypass surgery for ischemic cardiomyopathy.
This Viewpoint argues for a reconfiguration of the transition phase between hospital and home by extending active treatment beyond the acute care setting.
This Viewpoint discusses recent efforts to improve the low rates and quality of cardiopulmonary resuscitation (CPR) by bystanders in China via CPR training.
This review examines the historical basis for anticoagulant monitoring, discusses methods to measure and interpret drug levels, and critically assesses the role of routine laboratory monitoring in the management of non–vitamin K antagonist oral anticoagulant therapy.
A 30-year-old woman diagnosed with primary sclerosing cholangitis during pregnancy 5 years earlier was referred with severe hypercholesterolemia. She first noted the appearance of periorbital xanthelasmata 2 years after diagnosis of primary sclerosis cholangitis and developed marked worsening of biliary obstruction, deterioration of liver function, and clinical jaundice 6 months prior to referral. What would you do next?
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