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June 2019 - April 2016

Decade

Year

Issue

March 2019, Vol 4, No. 3, Pages 193-300

In This Issue of JAMA Cardiology

Highlights

Abstract Full Text
free access
JAMA Cardiol. 2019;4(3):193. doi:10.1001/jamacardio.2018.3185
Original Investigation

Association of Statin Adherence With Mortality in Patients With Atherosclerotic Cardiovascular Disease

Abstract Full Text
has audio
JAMA Cardiol. 2019;4(3):206-213. doi:10.1001/jamacardio.2018.4936

This cohort study explores the association of statin adherence with mortality in stable patients with atherosclerotic cardiovascular disease in the United States.

Association of Structural and Functional Cardiac Changes With Transcatheter Aortic Valve Replacement Outcomes in Patients With Aortic Stenosis

Abstract Full Text
JAMA Cardiol. 2019;4(3):215-222. doi:10.1001/jamacardio.2018.4830

This study describes a new tool for evaluating cardiac functions in patients with aortic stenosis who may need transcatheter aortic valve replacement.

Two-Year Outcomes After Transcatheter Aortic Valve Replacement With Mechanical vs Self-expanding Valves: The REPRISE III Randomized Clinical Trial

Abstract Full Text
JAMA Cardiol. 2019;4(3):223-229. doi:10.1001/jamacardio.2019.0091

This randomized clinical trial examines 2-year outcomes in all-cause mortality rates and all-cause mortality or disabling stroke for high-risk patients with aortic stenosis in North America, Europe, and Australia who received a mechically expanding valve vs a self-expanding valve.

Effect of Trimetazidine Dihydrochloride Therapy on Exercise Capacity in Patients With Nonobstructive Hypertrophic Cardiomyopathy: A Randomized Clinical Trial

Abstract Full Text
JAMA Cardiol. 2019;4(3):230-235. doi:10.1001/jamacardio.2018.4847

This randomized clinical trial at a tertiary referral center in the United Kingdom compares the effects of oral trimetazidine hydrochloride vs placebo on exercise capacity among patients with nonobstructive hypertrophic cardiomyopathy.

Survival Differences in Women and Men After Septal Myectomy for Obstructive Hypertrophic Cardiomyopathy

Abstract Full Text
JAMA Cardiol. 2019;4(3):237-245. doi:10.1001/jamacardio.2019.0084

This study of clinical data collected from 1961 to 2016 compares the preoperative characteristics and survival of women vs men undergoing septal myectomy for obstructive hypertrophic cardiomyopathy.

Association of Genetic and Clinical Aspects of Congenital Long QT Syndrome With Life-Threatening Arrhythmias in Japanese Patients

Abstract Full Text
JAMA Cardiol. 2019;4(3):246-254. doi:10.1001/jamacardio.2018.4925

This cohort study examines the association between sex and location of the long QT syndrome–related pathogenic variant as it pertains to the risk of life-threatening arrhythmias in Japanese patients.

Prognostic Value of Vasodilator Stress Cardiac Magnetic Resonance Imaging: A Multicenter Study With 48 000 Patient-Years of Follow-up

Abstract Full Text
JAMA Cardiol. 2019;4(3):256-264. doi:10.1001/jamacardio.2019.0035

This study examines whether stress cardiac magnetic resonance imaging is associated with patient mortality.

Differences in Management of Coronary Artery Disease in Patients With Medicare Advantage vs Traditional Fee-for-Service Medicare Among Cardiology Practices

Abstract Full Text
free access
JAMA Cardiol. 2019;4(3):265-271. doi:10.1001/jamacardio.2019.0007

This study using data from the Practice Innovation and Clinical Excellence (PINNACLE) registry investigated differences in evidence-based secondary prevention treatments and intermediate outcomes among patients with coronary artery disease enrolled in Medicare Advantage and fee-for-service Medicare.

Baseline Characteristics and Risk Profiles of Participants in the ISCHEMIA Randomized Clinical Trial

Abstract Full Text
JAMA Cardiol. 2019;4(3):273-286. doi:10.1001/jamacardio.2019.0014

This analysis of data from the International Study of Comparative Health Effectiveness With Medical and Invasive Approaches trial (ISCHEMIA) tdescribes baseline characteristics of participants enrolled and randomized in the trial and evaluates whether qualification by stress imaging or nonimaging exercise tolerance test influenced risk profiles.

Viewpoint

In-Hospital Initiation of Angiotensin Receptor-Neprilysin Inhibitors—The Time Is Now

Abstract Full Text
JAMA Cardiol. 2019;4(3):195-196. doi:10.1001/jamacardio.2019.0104

This Viewpoint describes randomized clinical trial data supporting the use of angiotensin receptor-neprilysin inhibitor medications as an alternative to angiotensin-converting enzyme medication regimens.

The Future of Registries in the Era of Real-world Evidence for Medical Devices

Abstract Full Text
JAMA Cardiol. 2019;4(3):197-198. doi:10.1001/jamacardio.2018.4933

This Viewpoint describes changes to the use of registries to evaluate medical devices.

Evaluating the Evidence for Coronary Computed Tomography Angiography as the Noninvasive Test of Choice for Patients With Stable Chest Pain

Abstract Full Text
JAMA Cardiol. 2019;4(3):199-200. doi:10.1001/jamacardio.2018.4332

This Viewpoint discusses the 2012 ACC/AHA Guideline for the Diagnosis and Management of Patients With Stable Ischemic Heart Disease and its recommendation for use of coronary computed tomography angiography for patients with a low to intermediate pretest probability of stable ischemic heart disease.

Editorial

What Is Needed Now to Improve Cardiovascular Clinical Registries in the Future

Abstract Full Text
JAMA Cardiol. 2019;4(3):201-202. doi:10.1001/jamacardio.2018.4946

Is the Search for Enough Moderate-Severe Ischemia Nearly Over?

Abstract Full Text
JAMA Cardiol. 2019;4(3):203-205. doi:10.1001/jamacardio.2019.0024
Invited Commentary

Nonobstructive Hypertrophic Cardiomyopathy—The High-Hanging Fruit

Abstract Full Text
JAMA Cardiol. 2019;4(3):235-236. doi:10.1001/jamacardio.2018.4953

Sex and Genotype in Long QT Syndrome Risk Stratification

Abstract Full Text
JAMA Cardiol. 2019;4(3):254-255. doi:10.1001/jamacardio.2018.4947

Observational Outcomes or Use of Guideline Recommended Treatments?Which Demonstrates Better Care?

Abstract Full Text
JAMA Cardiol. 2019;4(3):271-272. doi:10.1001/jamacardio.2019.0050
Review

Myocardial Strain in the Assessment of Patients With Heart Failure: A Review

Abstract Full Text
has active quiz has multimedia
JAMA Cardiol. 2019;4(3):287-294. doi:10.1001/jamacardio.2019.0052

This Review summarizes the utility of myocardial strain imaging in the assessment of risk prediction, diagnosis, treatment response, and follow-up of patients with heart failure.

JAMA Cardiology Clinical Challenge

Wide Complex Tachycardia and Syncope in a Middle-aged Woman

Abstract Full Text
has active quiz
JAMA Cardiol. 2019;4(3):295-296. doi:10.1001/jamacardio.2018.3687

A woman in her late 40s presents with palpitations with near syncope, monomorphic ventricular tachycardia, and multiple normal test results. What would you do next?

Comment & Response

Validity of a Novel Point-of-Care Troponin Assay for Single-Test Rule-Out of Acute Myocardial Infarction

Abstract Full Text
JAMA Cardiol. 2019;4(3):298. doi:10.1001/jamacardio.2018.4840

Validity of a Novel Point-of-Care Troponin Assay for Single-Test Rule-Out of Acute Myocardial Infarction—Reply

Abstract Full Text
JAMA Cardiol. 2019;4(3):298-299. doi:10.1001/jamacardio.2018.4843

Evaluating Treatment Effect of Transcatheter Interatrial Shunt Device Using Heart Failure Event Rates

Abstract Full Text
JAMA Cardiol. 2019;4(3):299. doi:10.1001/jamacardio.2019.0001

Evaluating Treatment Effect of Transcatheter Interatrial Shunt Device Using Heart Failure Event Rates—Reply

Abstract Full Text
JAMA Cardiol. 2019;4(3):299-300. doi:10.1001/jamacardio.2019.0004
Editor's Note

Statins Work, but Only in People Who Take Them

Abstract Full Text
JAMA Cardiol. 2019;4(3):214. doi:10.1001/jamacardio.2018.4948
JAMA Cardiology Masthead

JAMA Cardiology

Abstract Full Text
free access
JAMA Cardiol. 2019;4(3):194. doi:10.1001/jamacardio.2018.3186
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