This prespecified analysis of a randomized clinical trial evaluates the effect of evolocumab on total cardiovascular events.
This study combines data from multiple cohorts to assess the association of LPA variants with calcific aortic valve stenosis in patients undergoing heart surgery, patients with coronary artery disease, first-degree relatives of patients with coronary artery disease, and unrelated control participants.
This cohort study examines the excess risk of cardiovascular disease in women with a history of hypertensive disorders of pregnancy and estimates the proportion associated with conventional cardiovascular risk factors.
This cross-sectional analysis of an endurance exercise trial investigates the associations between dimethylguanidino valeric acid levels and metabolic health traits before and after 20 weeks of endurance exercise training.
This cohort study assesses the reliability of sudden cardiac death prediction methods leading to prophylactic implantable cardioverter/defibrillator recommendations to reduce the number of sudden cardiac deaths occurring in patients with hypertrophic cardiomyopathy.
This prespecified analysis of a randomized clinical trial assesses the outcome of all-comer patients with small coronary vessel lesions treated with 3 dissimilar types of drug-eluting stents.
This difference-in-differences analysis investigates the association of Medicaid expansion with cardiovascular mortality rates for middle-aged adults using data from 48 states and Washington, DC.
This study investigates whether mandatory reporting of CYP2C19 metabolizer status influence physicians’ decisions to switch P2Y12 inhibitors in the context of a clinical trial.
This cohort study uses data from a large blood donation program to estimate the prevalence of familial hypercholesterolemia in a population of more than 1 million individual donors with a total of more than 3 million blood donations.
This economic analysis uses an updated cost-effectiveness analysis of evolocumab added to standard therapy in patients with very high-risk atherosclerotic cardiovascular disease, reflecting new guidelines and a new evolocumab list price.
This analysis of data from the DEFINE-HF and BIOSTAT-CHF cohort studies defines and describes similarities and differences between iron deficiency due to low iron storage and defective iron utilization in patients with heart failure.
This Viewpoint discusses the influence social determinants of health have on shared decision-making between patients and clinicians regarding heart failure.
This essay describes a physician’s experience with making alterations to a patient’s do-not-resuscitate order.
This narrative review summarizes the findings of clinical trials that assess the value of losartan plus β-blockers vs either drug alone to prevent aortic dissections in patients with Marfan syndrome.
A woman in her early 60s with a history of hypertension, dyslipidemia, multiparity, and coronary angiogram 1 year prior presents with sudden onset of severe chest pain not alleviated by changing position and radiating to the left arm with concomitant nausea and diaphoresis. What would you do next?
This article describes the 2018 American College of Cardiology, American Heart Association, and Heart Rhythm Society Guideline on Bradycardia and Conduction Delay for patients who may need permanent pacing.
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