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April 2022 - April 2016

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Issue

January 2020, Vol 5, No. 1, Pages 3-112

In This Issue of JAMA Cardiology

Highlights

Abstract Full Text
free access
JAMA Cardiol. 2020;5(1):3. doi:10.1001/jamacardio.2019.3434
Original Investigation

Association of Genetically Predicted Lipid Levels With the Extent of Coronary Atherosclerosis in Icelandic Adults

Abstract Full Text
open access
JAMA Cardiol. 2020;5(1):13-20. doi:10.1001/jamacardio.2019.2946

This genetic study uses data from Icelandic adults who have been genotyped to estimate the contributions of genetically predicted blood lipid levels on the extent of coronary atherosclerosis.

Association of Sex With Outcomes in Patients Undergoing Percutaneous Coronary Intervention: A Subgroup Analysis of the GLOBAL LEADERS Randomized Clinical Trial

Abstract Full Text
free access
JAMA Cardiol. 2020;5(1):21-29. doi:10.1001/jamacardio.2019.4296

This study assesses the association of sex with patient outcomes at 2 years after contemporary percutaneous coronary intervention and with the efficacy and safety of 2 antiplatelet strategies.

Sex Differences in Cardiometabolic Traits and Determinants of Exercise Capacity in Heart Failure With Preserved Ejection Fraction

Abstract Full Text
free access
JAMA Cardiol. 2020;5(1):30-37. doi:10.1001/jamacardio.2019.4150

This cross-sectional study examines sex differences in cardiometabolic profiles and exercise hemodynamic profiles among individuals with heart failure with preserved ejection fraction.

Association of a P2Y12 Inhibitor Copayment Reduction Intervention With Persistence and Adherence With Other Secondary Prevention Medications: A Post Hoc Analysis of the ARTEMIS Cluster-Randomized Clinical Trial

Abstract Full Text
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JAMA Cardiol. 2020;5(1):38-46. doi:10.1001/jamacardio.2019.4408

This post hoc secondary analysis of a cluster-randomized trial assesses whether providing copayment reduction for P2Y12 inhibitors increases patient persistence in taking other secondary prevention cardiovascular medications.

Association of Pulmonary Hypertension With Clinical Outcomes of Transcatheter Mitral Valve Repair

Abstract Full Text
free access
JAMA Cardiol. 2020;5(1):47-56. doi:10.1001/jamacardio.2019.4428

This cohort study assesses the association of pulmonary hypertension with clinical outcomes in patients undergoing transcatheter mitral valve repair.

Association Between Obesity-Mediated Atrial Fibrillation and Therapy With Sodium Channel Blocker Antiarrhythmic Drugs

Abstract Full Text
free access
JAMA Cardiol. 2020;5(1):57-64. doi:10.1001/jamacardio.2019.4513

This cohort study examines the use of class I and class III antiarrhythmic drug treatment of atrial fibrillation in patients with obesity.

Association of Obesity With Adverse Long-term Outcomes in Hypertrophic Cardiomyopathy

Abstract Full Text
free access
JAMA Cardiol. 2020;5(1):65-72. doi:10.1001/jamacardio.2019.4268

This cohort study describes the association of body mass index with long-term outcomes in patients with hypertrophic cardiomyopathy in terms of overall disease progression, heart failure symptoms, and arrhythmias.

Mortality Among Referral Patients With Hypertrophic Cardiomyopathy vs the General European Population

Abstract Full Text
free access
JAMA Cardiol. 2020;5(1):73-80. doi:10.1001/jamacardio.2019.4534

This cohort study compares survival among the general European population with that of patients with hypertrophic cardiomyopathy who were recruited from 7 European specialty referral centers.

Association of Race With Disease Expression and Clinical Outcomes Among Patients With Hypertrophic Cardiomyopathy

Abstract Full Text
free access
JAMA Cardiol. 2020;5(1):83-91. doi:10.1001/jamacardio.2019.4638

This cohort study assesses the association between race, disease expression, care provision, and clinical outcomes among patients with hypertrophic cardiomyopathy.

Research Letter

High-Throughput, Contact-Free Detection of Atrial Fibrillation From Video With Deep Learning

Abstract Full Text
free access
JAMA Cardiol. 2020;5(1):105-107. doi:10.1001/jamacardio.2019.4004

This study uses video and a pretrained deep convolutional neural network to analyze facial photoplethysmographic signals in detection of atrial fibrillation.

Viewpoint

The March of Transcatheter Aortic Valve Replacement Therapy—US Food and Drug Administration Perspectives on Device Approval for Patients at Low Surgical Risk

Abstract Full Text
JAMA Cardiol. 2020;5(1):5-6. doi:10.1001/jamacardio.2019.4383

This Viewpoint describes the US Food and Drug Administration’s recent work on approving devices for transcatheter aortic valve replacement.

Transcatheter Aortic Valve Replacement for Patients at Low Surgical Risk—Selective or Ubiquitous?

Abstract Full Text
has audio
JAMA Cardiol. 2020;5(1):7-8. doi:10.1001/jamacardio.2019.4386

This Viewpoint summarizes data and recent decisions on transcatheter aortic valve replacement procedures for patients at low risk.

From the Heart

Tolstoy in Medicine

Abstract Full Text
JAMA Cardiol. 2020;5(1):11-12. doi:10.1001/jamacardio.2019.4545

This personal narrative discusses the convergence of literature and medicine by comparing Leo Tolstoy’s The Death of Ivan Ilyich with a real patient.

Editorial

Eliminating Wasteful Health Care Spending—Is the United States Simply Spinning Its Wheels?

Abstract Full Text
has multimedia
JAMA Cardiol. 2020;5(1):9-10. doi:10.1001/jamacardio.2019.4339
Invited Commentary

Determining Hypertrophic Cardiomyopathy Mortality: Gaining Wisdom From Knowledge

Abstract Full Text
JAMA Cardiol. 2020;5(1):81-82. doi:10.1001/jamacardio.2019.4548
Review

Adjunctive Antithrombotic Therapy for Patients With Aortic Stenosis Undergoing Transcatheter Aortic Valve Replacement

Abstract Full Text
has active quiz
JAMA Cardiol. 2020;5(1):92-101. doi:10.1001/jamacardio.2019.4367

This narrative review describes the risks and benefits of antithrombic therapy used with transcatheter aortic valve replacement for treatment of severe symptomatic aortic stenosis.

JAMA Cardiology Clinical Challenge

New-Onset Heart Failure in a Middle-aged Man

Abstract Full Text
has active quiz has multimedia
JAMA Cardiol. 2020;5(1):103-104. doi:10.1001/jamacardio.2019.4520

A man in his mid-60s presents with dyspnea with moderate levels of physical activity that are occasionally associated with brief episodes of lightheadedness, orthopnea, and tachypnea with a respiratory rate of 24 breaths per minute. What would you do next?

Cardiovascular Images

Man in His 90s With a History of Tachycardia and Abnormal Findings on Slitlamp Examination of the Cornea

Abstract Full Text
JAMA Cardiol. 2020;5(1):102. doi:10.1001/jamacardio.2019.4363

This case report describes corneal verticillata, a whorl-like pattern of brown or gray deposits in the inferior interpalpebral portion of the cornea.

Comment & Response

Heterogeneity Between Genetic Variants as a Proxy for Pleiotropy in Mendelian Randomization

Abstract Full Text
JAMA Cardiol. 2020;5(1):107-108. doi:10.1001/jamacardio.2019.4281

Heterogeneity Between Genetic Variants as a Proxy for Pleiotropy in Mendelian Randomization—Reply

Abstract Full Text
JAMA Cardiol. 2020;5(1):108. doi:10.1001/jamacardio.2019.4284

Beneficial Effects of Sunlight May Account for the Correlation Between Serum Vitamin D Levels and Cardiovascular Health

Abstract Full Text
JAMA Cardiol. 2020;5(1):109. doi:10.1001/jamacardio.2019.4336

Beneficial Effects of Sunlight May Account for the Correlation Between Serum Vitamin D Levels and Cardiovascular Health—Reply

Abstract Full Text
JAMA Cardiol. 2020;5(1):109-110. doi:10.1001/jamacardio.2019.4342

Silent Myocardial Infarction and Sudden Cardiac Death—Finding the Culprit

Abstract Full Text
JAMA Cardiol. 2020;5(1):110. doi:10.1001/jamacardio.2019.4377

Silent Myocardial Infarction and Sudden Cardiac Death—Finding the Culprit—Reply

Abstract Full Text
JAMA Cardiol. 2020;5(1):110-111. doi:10.1001/jamacardio.2019.4380

Clinical Considerations Prior to Transition From Triple Antithrombotic Therapy to Dual Antithrombotic Therapy

Abstract Full Text
JAMA Cardiol. 2020;5(1):111. doi:10.1001/jamacardio.2019.4542

Clinical Considerations Prior to Transition From Triple Antithrombotic Therapy to Dual Antithrombotic Therapy—Reply

Abstract Full Text
JAMA Cardiol. 2020;5(1):111-112. doi:10.1001/jamacardio.2019.4551
Editor's Note

Diagnosing With a Camera From a Distance—Proceed Cautiously and Responsibly

Abstract Full Text
JAMA Cardiol. 2020;5(1):107. doi:10.1001/jamacardio.2019.4572
Correction

Errors in Table 1 and Figures 2 and 3

Abstract Full Text
free access
JAMA Cardiol. 2020;5(1):112. doi:10.1001/jamacardio.2019.4472
JAMA Cardiology Masthead

JAMA Cardiology

Abstract Full Text
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JAMA Cardiol. 2020;5(1):4. doi:10.1001/jamacardio.2019.3435
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