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September 2021 - April 2016

Decade

Year

Issue

March 2021, Vol 6, No. 3, Pages 254-364

Original Investigation

Association of Low Plasma Transthyretin Concentration With Risk of Heart Failure in the General Population

Abstract Full Text
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JAMA Cardiol. 2021;6(3):258-266. doi:10.1001/jamacardio.2020.5969

This study evaluates whether low plasma transthyretin concentration is associated with incident heart failure in the general population.

Applicability of US Food and Drug Administration Labeling for Dapagliflozin to Patients With Heart Failure With Reduced Ejection Fraction in US Clinical Practice: The Get With the Guidelines–Heart Failure (GWTG-HF) Registry

Abstract Full Text
JAMA Cardiol. 2021;6(3):267-275. doi:10.1001/jamacardio.2020.5864

This cohort study evaluates candidacy for initiation of dapagliflozin based on the US Food and Drug Administration label among contemporary US patients with heart failure with reduced ejection fraction and describes potential barriers to therapeutic optimizations.

Associations of Adiposity, Circulating Protein Biomarkers, and Risk of Major Vascular Diseases

Abstract Full Text
open access
JAMA Cardiol. 2021;6(3):276-286. doi:10.1001/jamacardio.2020.6041

This subcohort study of Chinese adults examines the observational and genetic associations of adiposity with proteomics and the observational associations of adiposity with cardiovascular disease.

Clinical Utility of Lipoprotein(a) and LPA Genetic Risk Score in Risk Prediction of Incident Atherosclerotic Cardiovascular Disease

Abstract Full Text
open access
JAMA Cardiol. 2021;6(3):287-295. doi:10.1001/jamacardio.2020.5398

This study investigates whether a genetic risk score comprising 43 variants at the LPA gene, which encodes apolipoprotein(a), has clinical utility in assessing atherosclerotic cardiovascular disease risk compared with and in addition to lipoprotein(a) measurement.

Outcomes for Out-of-Hospital Cardiac Arrest in the United States During the Coronavirus Disease 2019 Pandemic

Abstract Full Text
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JAMA Cardiol. 2021;6(3):296-303. doi:10.1001/jamacardio.2020.6210

This registry-based study compares out-of-hospital cardiac arrest outcomes in the first few weeks of the coronavirus disease 2019 pandemic in 2020 with outcomes in the same period in 2019.

Objective Risk Assessment vs Standard Care for Acute Coronary Syndromes: A Randomized Clinical Trial

Abstract Full Text
JAMA Cardiol. 2021;6(3):304-313. doi:10.1001/jamacardio.2020.6314

This randomized clinical trial assesses the effect of routine Global Registries of Acute Coronary Events risk score implementation on guideline-indicated treatments and clinical outcomes of hospitalized patients with acute coronary syndrome.

Cardiac Structure and Function in Elite Female and Male Soccer Players

Abstract Full Text
JAMA Cardiol. 2021;6(3):316-325. doi:10.1001/jamacardio.2020.6088

This cross-sectional study describes electrocardiographic and echocardiographic findings in healthy elite US soccer players.

Brief Report

Outcomes of Percutaneous Trans–Right Atrial Access to the Left Ventricle for Catheter Ablation of Ventricular Tachycardia in Patients With Mechanical Aortic and Mitral Valves

Abstract Full Text
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JAMA Cardiol. 2021;6(3):326-331. doi:10.1001/jamacardio.2020.4414

This case series describes 4 patients who underwent a novel percutaneous trans-right atrial approach to accessing the left ventricle via a femoral venous approach for catheter ablation of ventricular tachycardia, meant specifically for patients with mechanical aortic and mitral valves.

Misclassification of Hospital Performance Under the Hospital Readmissions Reduction Program: Implications for Value-Based Programs

Abstract Full Text
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JAMA Cardiol. 2021;6(3):332-335. doi:10.1001/jamacardio.2020.4746

This cross-sectional study assesses whether hospitals were incorrectly penalized or incorrectly nonpenalized by the Hospital Readmissions Reduction Program for patient readmissions for acute myocardial infarction, heart failure, and pneumonia.

Association of Early-Life Trauma and Risk of Adverse Cardiovascular Outcomes in Young and Middle-aged Individuals With a History of Myocardial Infarction

Abstract Full Text
JAMA Cardiol. 2021;6(3):336-340. doi:10.1001/jamacardio.2020.5749

This cohort study investigates the association of early-life trauma with adverse events and examines whether inflammation plays a role.

Research Letter

Genetic Inhibition of PCSK9 and Liver Function

Abstract Full Text
JAMA Cardiol. 2021;6(3):353-354. doi:10.1001/jamacardio.2020.5341

This study investigates associations of the lifelong genetic inhibition of PCSK9 with plasma liver enzymes and nonalcoholic fatty liver disease by using the loss-of-function variant PCSK9-p.Arg46Leu as a genetic instrument.

Trends in Hospitalizations for Heart Failure and Ischemic Heart Disease Among US Adults With Diabetes

Abstract Full Text
JAMA Cardiol. 2021;6(3):354-357. doi:10.1001/jamacardio.2020.5921

This cohort study evaluates the association of heart failure and ischemic heart disease with diabetes complications.

Editorial

Misfolded Transthyretin as a Novel Risk Factor for Heart Failure: A Rich History With Implications for Future Diagnosis and Treatment

Abstract Full Text
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JAMA Cardiol. 2021;6(3):255-257. doi:10.1001/jamacardio.2020.5979
Invited Commentary

Risk Stratification Science Goes to a New Level

Abstract Full Text
JAMA Cardiol. 2021;6(3):314-315. doi:10.1001/jamacardio.2020.6325
Review

Mechanical Complications of Acute Myocardial Infarction: A Review

Abstract Full Text
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JAMA Cardiol. 2021;6(3):341-349. doi:10.1001/jamacardio.2020.3690

This narrative review discusses key clinical and diagnostic findings that may assist in the early diagnosis of mechanical complications and provides updates on current management strategies.

JAMA Cardiology Clinical Challenge

Urgent Need for Diagnosis of a Rapidly Growing Right Atrial Mass

Abstract Full Text
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JAMA Cardiol. 2021;6(3):350-351. doi:10.1001/jamacardio.2020.6107

A patient presents with progressive shortness of breath, a productive cough, fatigue, weight loss, and night sweats for several months. A transthoracic echocardiogram revealed a right atrial mass. What would you do next?

Comment & Response

QT Interval in Patients With COVID-19

Abstract Full Text
JAMA Cardiol. 2021;6(3):357. doi:10.1001/jamacardio.2020.4952

QT Interval in Patients With COVID-19

Abstract Full Text
JAMA Cardiol. 2021;6(3):357-358. doi:10.1001/jamacardio.2020.4955

QT Interval in Patients With COVID-19—Reply

Abstract Full Text
JAMA Cardiol. 2021;6(3):358. doi:10.1001/jamacardio.2020.4958

Complications in Patients With COVID-19

Abstract Full Text
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JAMA Cardiol. 2021;6(3):359. doi:10.1001/jamacardio.2020.5788

Complications in Patients With COVID-19

Abstract Full Text
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JAMA Cardiol. 2021;6(3):359-360. doi:10.1001/jamacardio.2020.5791

Complications in Patients With COVID-19—Reply

Abstract Full Text
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JAMA Cardiol. 2021;6(3):360. doi:10.1001/jamacardio.2020.5794

Exploring the Cardiac Phenotypes of Prematurity

Abstract Full Text
JAMA Cardiol. 2021;6(3):361. doi:10.1001/jamacardio.2020.6056

Exploring the Cardiac Phenotypes of Prematurity—Reply

Abstract Full Text
JAMA Cardiol. 2021;6(3):361-362. doi:10.1001/jamacardio.2020.6059

Venoarterial Extracorporeal Membrane Oxygenation to Heart Transplant—An Inflamed Bridge?

Abstract Full Text
JAMA Cardiol. 2021;6(3):362. doi:10.1001/jamacardio.2020.6115

Venoarterial Extracorporeal Membrane Oxygenation to Heart Transplant—An Inflamed Bridge?—Reply

Abstract Full Text
JAMA Cardiol. 2021;6(3):362-363. doi:10.1001/jamacardio.2020.6127

Cost-effectiveness of Statin Use Guidelines

Abstract Full Text
JAMA Cardiol. 2021;6(3):363-364. doi:10.1001/jamacardio.2020.6121

Cost-effectiveness of Statin Use Guidelines—Reply

Abstract Full Text
JAMA Cardiol. 2021;6(3):364. doi:10.1001/jamacardio.2020.6130
JAMA Cardiology Masthead

JAMA Cardiology

Abstract Full Text
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JAMA Cardiol. 2021;6(3):254. doi:10.1001/jamacardio.2020.4540
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