This diagnostic study tests whether nurses who were naive to ultrasonographic use could obtain 10-view transthoracic echocardiographic studies of diagnostic quality using deep-learning artificial intelligence–based software.
This cohort study evaluates whether contemporary machine learning methods can facilitate prediction of death from acute myocardial infarction by including a larger number of variables and identifying complex relationships between predictors and outcomes.
This longitudinal cohort study assesses whether posttraumatic stress disorder is associated with incident ischemic heart disease in US women veterans.
This cohort study examines the metabolic cost of initiating exercise and its functional consequences.
This cohort study determines the relative association of non–high-density lipoprotein cholesterol levels at different life stages for the presence of coronary artery calcification in mid-adulthood.
This study derives and validates a 4-level pretest probability rule that makes it possible to rule out pulmonary embolism solely on clinical criteria and optimized D-dimer measurement to safely decrease imaging testing for suspected pulmonary embolism.
This prespecified secondary analysis of a randomized clinical trial investigates the efficacy and safety of dapagliflozin compared with placebo in men and women with heart failure with reduced ejection fraction enrolled in the Dapagliflozin and Prevention of Adverse Outcomes in Heart Failure trial.
This cohort study examines the addition of self-reported leisure-time physical activity to pooled cohort equations in risk prediction models of atherosclerotic cardiovascular disease.
This systematic review and meta-analysis of 6 randomized clinical trials evaluates the safety and efficacy of atrial fibrillation ablation as first-line therapy compared with antiarrhythmic drugs in patients with paroxysmal atrial fibrillation.
This secondary analysis of the Vericiguat Global Study in Subjects With Heart Failure With Reduced Ejection Fraction clinical trial evaluates clinical characteristics, outcomes, and treatment response to vericiguat according to prespecified index event subgroups and time from index heart failure hospitalization.
This cross-sectional study assesses the national prevalence of financial hardship because of medical bills among families of children with congenital heart disease in the US and the association of financial hardship with adverse outcomes.
This cross-sectional study of Black participants in the Coronary Artery Risk Development in Young Adults cohort examines the association between the V122I TTR genetic variant and cardiac structure and function in middle age in those without heart failure.
This essay discusses the aging process among physicians and the need to assess physician cognitive and sensorineural competence as indicated on an individual basis regardless of age.
A previously healthy middle-aged man is diagnosed with respiratory failure requiring venovenous extracorporeal membrane oxygenation. Imaging showed abnormalities in the right coronary artery. What would you do next?