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Day

July 28, 2021
Original Investigation

Contemporaneous Comparison of Outcomes Among Patients Implanted With a Leadless vs Transvenous Single-Chamber Ventricular Pacemaker

Abstract Full Text
JAMA Cardiol. Published online July 28, 2021. doi:10.1001/jamacardio.2021.2621

This cohort study compares patient characteristics and complications among patients implanted with leadless VVI and transvenous VVI pacemakers.

Extrapolating Long-term Event-Free and Overall Survival With Dapagliflozin in Patients With Heart Failure and Reduced Ejection Fraction: An Exploratory Analysis of a Phase 3 Randomized Clinical Trial

Abstract Full Text
JAMA Cardiol. Published online July 28, 2021. doi:10.1001/jamacardio.2021.2632

This exploratory analysis of a randomized clinical trial extrapolates findings to estimate event-free and overall survival time with long-term dapagliflozin therapy in patients with heart failure and reduced ejection fraction.

Invited Commentary

Extrapolating Survival From Randomized Clinical Trial Data—Possibilities and Caution

Abstract Full Text
JAMA Cardiol. Published online July 28, 2021. doi:10.1001/jamacardio.2021.2629
July 21, 2021
Original Investigation

Exercise Capacity in Young Adults Born Small for Gestational Age

Abstract Full Text
has multimedia
JAMA Cardiol. Published online July 21, 2021. doi:10.1001/jamacardio.2021.2537

This cohort study assesses exercise capacity and baseline cardiac structure and function among young adults born with a birth weight below the 10th centile (small for gestational age).

Research Letter

Population Trends in Rates of Percutaneous Coronary Interventions, 2010 to 2017

Abstract Full Text
JAMA Cardiol. Published online July 21, 2021. doi:10.1001/jamacardio.2021.2639

This study provides a contemporary assessment of population-level trends in percutaneous coronary intervention use among all age groups, insurance payers, and hospital settings across 4 US states.

JAMA Cardiology Clinical Guidelines Synopsis

Guideline Update on Indications for Transcatheter Aortic Valve Implantation Based on the 2020 American College of Cardiology/American Heart Association Guidelines for Management of Valvular Heart Disease

Abstract Full Text
JAMA Cardiol. Published online July 21, 2021. doi:10.1001/jamacardio.2021.2534

This guideline synopsis summarizes 2020 improvements to the American College of Cardiology/American Heart Association Guidelines for Management of Valvular Heart Disease.

July 14, 2021
Original Investigation

Effect of Paroxetine-Mediated G-Protein Receptor Kinase 2 Inhibition vs Placebo in Patients With Anterior Myocardial Infarction: A Randomized Clinical Trial

Abstract Full Text
JAMA Cardiol. Published online July 14, 2021. doi:10.1001/jamacardio.2021.2247

This double-blind, placebo-controlled randomized clinical trial investigates the efficacy of paroxetine-mediated G-protein–coupled receptor kinase 2 inhibition to mitigate adverse left ventricular remodeling in patients with acute myocardial infarction.

Assessment of Coronary Artery Calcium Scoring to Guide Statin Therapy Allocation According to Risk-Enhancing Factors: The Multi-Ethnic Study of Atherosclerosis

Abstract Full Text
JAMA Cardiol. Published online July 14, 2021. doi:10.1001/jamacardio.2021.2321

This cross-sectional study examines the association between risk-enhancing factors and incident atherosclerotic cardiovascular disease by coronary artery calcium burden among intermediate-risk adults who participated in the Multi-Ethnic Study of Atherosclerosis.

Special Communication

Posttraumatic Stress Disorder and Cardiovascular Disease: State of the Science, Knowledge Gaps, and Research Opportunities

Abstract Full Text
has audio
JAMA Cardiol. Published online July 14, 2021. doi:10.1001/jamacardio.2021.2530

This study critically reviews the available evidence on the association of posttraumatic stress disorder with cardiovascular disease from population, basic, and genomic research as well as from clinical and translational research.

July 7, 2021
Original Investigation

Association of Mitral Annular Disjunction With Cardiovascular Outcomes Among Patients With Marfan Syndrome

Abstract Full Text
has multimedia
JAMA Cardiol. Published online July 7, 2021. doi:10.1001/jamacardio.2021.2312

This cohort study examines the prevalence of mitral annular disjunction and examine its association with cardiovascular outcomes and arrhythmia among patients with Marfan syndrome.

Review

Clinical Strategy for the Diagnosis and Treatment of Immune Checkpoint Inhibitor–Associated Myocarditis: A Narrative Review

Abstract Full Text
JAMA Cardiol. Published online July 7, 2021. doi:10.1001/jamacardio.2021.2241

This narrative review provides an overview of the diagnostic and therapeutic approach for patients with suspected immune checkpoint inhibitor–associated myocarditis.

Comment & Response

Reporting of Percutaneous Coronary Interventions Site-Specific Mortality

Abstract Full Text
JAMA Cardiol. Published online July 7, 2021. doi:10.1001/jamacardio.2021.2105

Reporting of Percutaneous Coronary Interventions Site-Specific Mortality—Reply

Abstract Full Text
JAMA Cardiol. Published online July 7, 2021. doi:10.1001/jamacardio.2021.2108
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