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Year

Day

April 29, 2020
Original Investigation

Performance of Hospitals When Assessing Disease-Based Mortality Compared With Procedural Mortality for Patients With Acute Myocardial Infarction

Abstract Full Text
JAMA Cardiol. Published online April 29, 2020. doi:10.1001/jamacardio.2020.0753

This cross-sectional study examines correlation and reclassification between hospital-level disease-specific mortality and percutaneous coronary intervention procedural mortality among patients with acute myocardial infarction.

Effect of Evolocumab on Type and Size of Subsequent Myocardial Infarction: A Prespecified Analysis of the FOURIER Randomized Clinical Trial

Abstract Full Text
JAMA Cardiol. Published online April 29, 2020. doi:10.1001/jamacardio.2020.0764

This prespecified analysis of a randomized clinical trial evaluates the effect of evolocumab on type and size of subsequent myocardial infarction.

Brief Report

An Exploratory Analysis of Proprotein Convertase Subtilisin/Kexin Type 9 Inhibition and Aortic Stenosis in the FOURIER Trial

Abstract Full Text
JAMA Cardiol. Published online April 29, 2020. doi:10.1001/jamacardio.2020.0728

This exploratory analysis of a randomized clinical trial aims to determine whether evolocumab reduces the risk of aortic stenosis events in patients with atherosclerotic cardiovascular disease.

Editorial

Preventing Aortic Stenosis by Changing the Way We Think About an Old Disease

Abstract Full Text
JAMA Cardiol. Published online April 29, 2020. doi:10.1001/jamacardio.2020.0722
Invited Commentary

Toward a More Detailed Reporting of MI Reduction in Clinical Trials—A Welcome and Needed Step in the Right Direction

Abstract Full Text
JAMA Cardiol. Published online April 29, 2020. doi:10.1001/jamacardio.2020.0749
Cardiovascular Images

A Man in His 80s With Dyspnea and a Malpositioned Pacemaker Lead

Abstract Full Text
JAMA Cardiol. Published online April 29, 2020. doi:10.1001/jamacardio.2020.0647

This case report describes a lead entering the left atrium via the right upper pulmonary vein through a large sinus venosus atrial septal defect with a dilated right heart and substantial left-to-right shunt.

April 23, 2020
Brief Report

Association of Renin-Angiotensin System Inhibitors With Severity or Risk of Death in Patients With Hypertension Hospitalized for Coronavirus Disease 2019 (COVID-19) Infection in Wuhan, China

Abstract Full Text
free access
JAMA Cardiol. Published online April 23, 2020. doi:10.1001/jamacardio.2020.1624

This cohort study examines the association between angiotensin-converting enzyme inhibitors/angiotensin receptor blockers and severity of illness and mortality in patients with hypertension hospitalized for COVID-19 infection.

April 22, 2020
Original Investigation

Off-label Use of Direct Oral Anticoagulants Compared With Warfarin for Left Ventricular Thrombi

Abstract Full Text
JAMA Cardiol. Published online April 22, 2020. doi:10.1001/jamacardio.2020.0652

This cohort study compares the outcomes associated with direct oral anticoagulant use and warfarin use for the treatment of left ventricular thrombi.

Assessment of Limitations to Optimization of Guideline-Directed Medical Therapy in Heart Failure From the GUIDE-IT Trial: A Secondary Analysis of a Randomized Clinical Trial

Abstract Full Text
JAMA Cardiol. Published online April 22, 2020. doi:10.1001/jamacardio.2020.0640

This secondary analysis of a randomized clinical trial examines medical therapy and reasons why an intervention did not work for patients with heart failure in the Guiding Evidence-Based Therapy Using Biomarker Intensified Treatment.

Comment & Response

Initial Monthly Cost of Tafamidis—the Real Price for Patients

Abstract Full Text
JAMA Cardiol. Published online April 22, 2020. doi:10.1001/jamacardio.2020.0863

Initial Monthly Cost of Tafamidis—the Real Price for Patients—Reply

Abstract Full Text
JAMA Cardiol. Published online April 22, 2020. doi:10.1001/jamacardio.2020.0866
Editor's Note

High Rates of Off-label Prescribing and the Urgent Need for a Randomized Clinical Trial

Abstract Full Text
JAMA Cardiol. Published online April 22, 2020. doi:10.1001/jamacardio.2020.0612
April 15, 2020
Original Investigation

Strategies of Wait-listing for Heart Transplant vs Durable Mechanical Circulatory Support Alone for Patients With Advanced Heart Failure

Abstract Full Text
JAMA Cardiol. Published online April 15, 2020. doi:10.1001/jamacardio.2020.0631

This national registry-based cohort study assesses whether left ventricular assist device destination therapy is associated with survival benefit comparable to wait-listing for heart transplant with or without left ventricular assist device therapy for bridge to transplant indication among patients with advanced heart failure.

Transplant Center Variability in Organ Offer Acceptance and Mortality Among US Patients on the Heart Transplant Waitlist

Abstract Full Text
JAMA Cardiol. Published online April 15, 2020. doi:10.1001/jamacardio.2020.0659

This cohort study examines mortality among US patients on the heart transplant waitlist among transplant centers with varying allograft acceptance rates.

Association Between Visit-to-Visit Blood Pressure Variability in Early Adulthood and Myocardial Structure and Function in Later Life

Abstract Full Text
JAMA Cardiol. Published online April 15, 2020. doi:10.1001/jamacardio.2020.0799

This cohort study examines the association between blood pressure variability in early adulthood and myocardial structure and function in middle age.

Brief Report

Use of Temporary Mechanical Circulatory Support for Management of Cardiogenic Shock Before and After the United Network for Organ Sharing Donor Heart Allocation System Changes

Abstract Full Text
JAMA Cardiol. Published online April 15, 2020. doi:10.1001/jamacardio.2020.0692

This cohort study examines the association of revisions to the United Network for Organ Sharing donor heart allocation system with use of temporary mechanical circulatory support and whether temporary mechanical circulatory support use differed between US transplant centers and US nontransplant centers and Canadian centers.

Research Letter

Trends in Mechanical Support Use as a Bridge to Adult Heart Transplant Under New Allocation Rules

Abstract Full Text
JAMA Cardiol. Published online April 15, 2020. doi:10.1001/jamacardio.2020.0667

This study investigates trends in mechanical support use after implementation of the Organ Procurement and Transplantation Network’s new heart transplant allocation rules.

Editorial

Anticipating a New Era in Heart Transplantation

Abstract Full Text
JAMA Cardiol. Published online April 15, 2020. doi:10.1001/jamacardio.2020.0611
April 8, 2020
Original Investigation

Long-term Outcomes in Patients With Severely Reduced Left Ventricular Ejection Fraction Undergoing Percutaneous Coronary Intervention vs Coronary Artery Bypass Grafting

Abstract Full Text
JAMA Cardiol. Published online April 8, 2020. doi:10.1001/jamacardio.2020.0239

This cohort study compares long-term outcomes in patients undergoing revascularization by percutaneous coronary intervention vs coronary artery bypass grafting.

Omission of Heart Transplant Recipients From the Appropriate Use Criteria for Revascularization and the Ramifications on Heart Transplant Centers

Abstract Full Text
JAMA Cardiol. Published online April 8, 2020. doi:10.1001/jamacardio.2020.0586

This study assesses the rate of rarely appropriate percutaneous coronary intervention (PCI) procedures in heart transplant recipients and its association with hospital PCI appropriateness metrics and pay-for-performance scorecards.

Viewpoint

The Conundrum and Opportunity of Gender Equity For Evidence Generators

Abstract Full Text
JAMA Cardiol. Published online April 8, 2020. doi:10.1001/jamacardio.2020.0594

This Viewpoint discusses why and how women should have a larger leadership roles across all areas of medicine, including industry.

Invited Commentary

Percutaneous Coronary Intervention or Coronary Artery Bypass Grafting to Treat Ischemic Cardiomyopathy?

Abstract Full Text
JAMA Cardiol. Published online April 8, 2020. doi:10.1001/jamacardio.2020.0597
April 3, 2020
Viewpoint

Coronavirus Disease 2019 (COVID-19) Infection and Renin Angiotensin System Blockers

Abstract Full Text
free access has active quiz
JAMA Cardiol. Published online April 3, 2020. doi:10.1001/jamacardio.2020.1282

This Viewpoint discusses recommendations for angiotensin-converting enzyme inhibitor and angiotensin receptor blocker use in patients with or at risk of contracting coronavirus disease 2019 (COVID-19).

The Dilemma of Coronavirus Disease 2019, Aging, and Cardiovascular Disease: Insights From Cardiovascular Aging Science

Abstract Full Text
free access has active quiz
JAMA Cardiol. Published online April 3, 2020. doi:10.1001/jamacardio.2020.1329

This Viewpoint discusses whether individuals should continue to take angiotensin-converting enzyme inhibitors and angiotensin receptor blockers in the context of coronavirus disease 2019 (COVID-19).

April 1, 2020
Original Investigation

Association of Rare PTGIS Variants With Susceptibility and Pulmonary Vascular Response in Patients With Idiopathic Pulmonary Arterial Hypertension

Abstract Full Text
open access
JAMA Cardiol. Published online April 1, 2020. doi:10.1001/jamacardio.2020.0479

This genetic association study assesses novel susceptibility genes other than BMPR2 in patients with idiopathic pulmonary arterial hypertension.

Research Letter

Access to Transcatheter Aortic Valve Replacement Under New Medicare Surgical Volume Requirements

Abstract Full Text
JAMA Cardiol. Published online April 1, 2020. doi:10.1001/jamacardio.2020.0443

This cohort study examines the frequency and characteristics of non–transcatheter aortic valve replacement (TAVR) hospitals that do or do not meet new surgical volume requirements compared with TAVR hospitals.

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