Author Affiliations: Department of Dermatology, University of California, San Francisco, San Francisco, California (Drs Park Murase); Department of Dermatology, Palo Alto Foundation Medical Group, Mountain View, California (Dr Murase).
We read with interest Zeichner ’s1 case report of acne vulgaris during pregnancy treated successfully with narrowband UV-B (NB-UV-B) therapy. Generally, UV-B is considered a safe form of psoriasis therapy during pregnancy, and this may apply to acne treatment as well. However, it is of utmost importance not to overlook the photodegradation of folic acid associated with light therapy.
Kelly K. Park, Jenny E. Murase. Narrowband UV-B Phototherapy During Pregnancy and Folic Acid Depletion. Arch Dermatol. 2012;148(1):132–133. doi:10.1001/archdermatol.2011.1614