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Mar 2012

A Firm Nodule on the Glabella With Recurrent Facial Edema —Diagnosis

Author Affiliations
 

SECTION EDITOR: MARY S. STONE, MD; ASSISTANT SECTION EDITORS: SOON BAHRAMI, MD; CARRIE ANN R. CUSACK, MD; SENAIT W. DYSON, MD; MOLLY A. HINSHAW, MD; ARNI K. KRISTJANSSON, MD

Arch Dermatol. 2012;148(3):385-390. doi:10.1001/archderm.148.3.385-h

Histopathologic examination of the skin biopsy specimens showed numerous microvacuoles of varying size within the subcutaneous tissue and an associated focal granulomatous infiltrate. These findings represent changes due to injection of exogenous material, as seen in a paraffinoma. At a follow-up visit, the patient was questioned again about any history of local injections and revealed that an unknown substance had been injected in multiple areas of her face 7 years earlier while she was living outside the United States. The diagnosis of paraffinoma was made.

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