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Society Transactions
April 1959


AMA Arch Derm. 1959;79(4):484-495. doi:10.1001/archderm.1959.01560160102016

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Diagnosis: I. Extracellular Cholesterosis; II. Follow-Up Report of a Proven Case of Extracellular Cholesterosis. Presented by Dr. Julius H. Pollock and Dr. Nathan Sobel.

I. The patient presented is a 43-year-old housewife who was first seen about 8 months ago with a complaint of a painful, progressive, and recurrent eruption limited mainly to the extremities and of one year's duration. Examination of the patient at that time revealed a middle-aged woman apparently in good general health but for the dermatosis that had the following important features:

  • Lesions that were of recent development had morphologic characteristics of erythema multiforme; namely, macules of erythema, plaques of edema, and gradations of these processes up to vesicles and bullae. Unlike erythema multiforme, these lesions were very tender and painful.

  • Older lesions were nodules or plaques of brown color, of dime- to nickel-piece size, but slightly elevated and

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