SECTION EDITOR: MARY S. STONE, MD; ASSISTANT SECTION EDITORS: SOON BAHRAMI, MD; CARRIE ANN R. CUSACK, MD; SENAIT W. DYSON, MD; MOLLY A. HINSHAW, MD; ARNI K. KRISTJANSSON, MD
The biopsy specimen of a papular lesion revealed dermal aggregates of histiocytes, foamy histiocytes, and occasional Touton giant cells. There was a surrounding mixed-cell infiltrate. The biopsy specimen of a macular lesion showed similar but smaller dermal aggregates of histiocytes with scattered lymphocytes and rare eosinophils. These findings were consistent with JXGs.
The results of ophthalmologic evaluation were normal, including no JXGs or hamartomas of the iris. Laboratory tests, including a complete blood cell count with differential, fasting lipid panel, basic metabolic profile, serum protein electrophoresis, urinalysis, and urinary and serum osmolality, demonstrated no abnormalities. A radiologic skeletal survey revealed no destructive lesions or other focal bony abnormality. Given the lack of available therapies, clinical follow-up was recommended in 6 months. At her follow-up visit, the patient was noted to have developed a few new lesions, without any changes in the existing lesions.
Multiple Brown Macules and Papules on a Female Teenager—Diagnosis. Arch Dermatol. 2012;148(4):531–536. doi:10.1001/archderm.148.4.532-d
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