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June 2012

Perinatal Cytomegalovirus-Associated Bullae in an Immunocompetent Infant

Author Affiliations

Author Affiliations: Departments of Dermatology (Drs Yasuda, Sugiura, and Akiyama) and Virology (Dr Kimura), Nagoya University Graduate School of Medicine, Nagoya, Japan; Departments of Dermatology (Dr Ishikawa and Kihira) and Pediatrics (Dr Negishi), Gifu Prefectural Tajimi Hospital, Tajimi, Japan; Department of Pediatrics, Nagoya City University, Graduate School of Medical Science, Nagoya (Drs Iwayama and Ito); and Department of Pathology, Hamamatsu Medical University School of Medicine, Hamamatsu, Japan (Dr Kosugi).

Arch Dermatol. 2012;148(6):770-772. doi:10.1001/archdermatol.2011.3258

Although perinatal cytomegalovirus (CMV) infection is common, symptomatic CMV infection is a rare complication in immunocompetent infants. We describe herein CMV-associated bullae accompanied by CMV hepatitis in an immunocompetent newborn infant is reported.

Report of a Case

The patient was a 1-month-old female infant of 39 weeks' gestation and vaginal delivery with no apparent complications. She presented with a history of crops of vesicles and bullae on the face, precordial area, and buttocks that began appearing at age 3 weeks and continued to appear. The lesions manifested as multiple 10-mm-diameter bullae with several crusts on the sites (Figure 1A and B).