Commentary on: Atopic dermatitis and the hygiene hypothesis revisitedFlohr C, Yeo L Curr Probl Dermatol. 2011;41:1-34
Question: Is there evidence to support an association between atopic dermatitis (AD) and hygiene as it relates to microbial burden? Does the literature support a link between any particular infectious or anti-infectious (ie, antibiotics, vaccinations) agent and AD?
Data Sources: A systematic review of the literature was performed using studies identified via a MEDLINE search from 1966 until June 2010. Search findings were supplemented by a hand search of references contained within studies located by MEDLINE search. 49 new studies were deemed suitable for inclusion.