A 22-year-old male amateur bodybuilder presented to our clinic with a 3-month history of severe acne lesions on his upper trunk and face, accompanied by arthralgia of several joints. He reported the use of anabolic androgenic steroids (AAS) (testosterone enanthate, trenbolone acetate, drostanolone propionate, and methandrostenolone) for 3 months to increase his muscle mass. Shortly after he discontinued AAS intake, he developed severe inflammatory acne with painful rupturing and draining inflammatory nodules, pustules, and hemorrhagic ulcerations on his upper trunk and face (Figure, A and B). Moreover, he described an immobilizing arthralgia of his right ankle and both shoulder joints, as well as general symptoms including fatigue and a 15-kg weight loss over the 6 weeks prior to presentation.