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Oct 2012

Erythematous Eruption With Marked Conjunctival Injection—Diagnosis

Author Affiliations
 

SECTION EDITOR: MARY S. STONE, MD; ASSISTANT SECTION EDITORS: SOON BAHRAMI, MD; CARRIE ANN R. CUSACK, MD; SENAIT W. DYSON, MD; MOLLY A. HINSHAW, MD; ARNI K. KRISTJANSSON, MD

Arch Dermatol. 2012;148(10):1200. doi:10.1001/archderm.148.10.1200-d

The biopsy specimen displayed a dense superficial and deep nodular perivascular infiltrate of medium-sized lymphocytes, many with nuclear irregularity and prominent nucleoli (Figure 3). Immunohistochemical evaluation demonstrated strong anti-CD3 and CD4 staining of all neoplastic cells. Anti-CD7 staining was diffuse but faint. Anti-CD8, CD20, T-cell leukemia/lymphoma 1 (TCL-1), and terminal deoxynucleotidyl transferase (TdT) did not stain neoplastic cells. Bacterial, mycobacterial, and fungal stains were all negative.

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