Circumscribed acral hypokeratosis (CAH) is a rare benign dermatosis of unknown origin first described in 2002.1 This uncommon dermatosis is seen predominantly on the palms of adult women with a mean age of 65 years.2 Lesions have a predilection for the thenar or hypothenar eminence of the predominant palm and less frequently on the soles. Typically, the lesions are solitary, but multiple lesions have been reported.
Butler LK, Kiracofe EA, Marks VJ. Circumscribed Acral Hypokeratosis: Successful Treatment of a Potentially Premalignant Condition. Arch Dermatol. 2012;148(12):1427–1428. doi:10.1001/archdermatol.2012.2919
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