SECTION EDITOR: MARY S. STONE, MD; ASSISTANT SECTION EDITORS: SOON BAHRAMI, MD; CARRIE ANN R. CUSACK, MD; MOLLY A. HINSHAW, MD; ARNI K. KRISTJANSSON, MD; LORI D. PROK, MD
Histopathologic evaluation of several lesions revealed a dermal proliferation of moderately dilated capillaries lined by flattened endothelial cells, consistent with a capillary hemangioma (Figure 2). Other lesions demonstrated large, interconnected spaces containing red blood cells and lined by a single layer of thin endothelial cells, suggestive of a venous malformation (Figure 3). Gene sequencing revealed a mutation in the KRIT protein of the CCM1 gene, which provided additional diagnostic confirmation.
Blue Papules in a Patient With Neurologic Symptoms—Diagnosis. JAMA Dermatol. 2013;149(1):98. doi:10.1001/2013.jamadermatol.683b
* * SCHEDULED MAINTENANCE * *
The JAMA Network Sites will be conducting routine maintenance from 10/20/2017 through 10/21/2017. During this window access to content and authentication may be intermittently available. The JAMA Store will be completely unavailable during the maintenance window.