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January 2013

Eruption in a Patient With Crohn Disease—Diagnosis

Author Affiliations
 

SECTION EDITOR: MARY S. STONE, MD; ASSISTANT SECTION EDITORS: SOON BAHRAMI, MD; CARRIE ANN R. CUSACK, MD; MOLLY A. HINSHAW, MD; ARNI K. KRISTJANSSON, MD; LORI D. PROK, MD

JAMA Dermatol. 2013;149(1):98. doi:10.1001/2013.jamadermatol.206b

A skin biopsy specimen demonstrated an inflammatory infiltration that was mainly perifollicular in distribution and consisted of eosinophils and neutrophils. Treatment was initiated with oral prednisone (60 mg/d), wet compresses, and fusidic acid cream. After the disease activity was suppressed, the corticosteroid dose was tapered and isotretinoin was added to the regimen, with a marked improvement of the lesions. The patient tolerated the isotretinoin therapy well, without reactivation of his Crohn disease.

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