SECTION EDITOR: MARY S. STONE, MD; ASSISTANT SECTION EDITORS: SOON BAHRAMI, MD; CARRIE ANN R. CUSACK, MD; MOLLY A. HINSHAW, MD; ARNI K. KRISTJANSSON, MD; LORI D. PROK, MD
A 7-year-old girl presented with complaints of hair loss and a known partial biotinidase deficiency since birth. Biotin supplementation was discontinued after the first year of life because clinical manifestations were absent, and laboratory findings were normal. At age 2 years, hair loss and eczema occurred. Owing to low biotinidase activity, biotin supplementation, 20 mg/wk, was restarted, but it was again discontinued at age 3 years because normal biotin levels had been achieved once more.
Lünnemann L, Vogt A, Blume-Peytavi U, Bartels NG. Hair-Shaft Abnormality in a 7-Year-Old Girl—Quiz Case. JAMA Dermatol. 2013;149(3):358–363. doi:10.1001/jamadermatol.2013.1490a
Browse and subscribe to JAMA Network podcasts!
Customize your JAMA Network experience by selecting one or more topics from the list below.
Create a personal account or sign in to: