A 30-year-old man presented with a 7-year history of a slowly growing, firm nodule on the left forearm. The lesion had never bled or caused discomfort, and the patient denied paresthesias of the forearm or hand. His medical history was otherwise unremarkable. The physical examination revealed a 3.5 × 2.5-cm indurated, subcutaneous nodule with hypertrichosis and central, cerebriform texture (Figure 1). Palpation of the surrounding skin revealed clinically significant nontender deep induration. Representative histopathologic features from surgical excision are shown in Figure 2 and Figure 3.
Marchetti MA, Russell M. Solitary Cerebriform Nodule—Quiz Case. JAMA Dermatol. 2013;149(5):609–614. doi:10.1001/jamadermatol.2013.3058a
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