A 10-year-old previously healthy African American girl presented with a 1-year history of skin discoloration of her right cheek; it had progressively been enlarging and becoming painful several months prior to presentation. One month prior to dermatological evaluation, she was empirically treated with amoxicillin for a sore throat with associated lymphadenopathy. She had recently noted intermittent and more frequent nosebleeds. She was not receiving any medications and denied weight loss or other constitutional symptoms. Her primary care physician had performed screening laboratory studies, including complete blood cell count, comprehensive metabolic panel, and antinuclear antibody test, all of which had normal results.
Little AJ, Martinez-Diaz GJ, Gehris RP. Solitary, Enlarging Painful Violaceous Tumor on the Cheek of a 10-Year-Old—Quiz Case. JAMA Dermatol. 2013;149(5):609–614. doi:10.1001/jamadermatol.2013.3053a
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