The year 1979 marked the first publication that used the term subacute cutaneous lupus erythematosus (SCLE).1 Six years later, in 1985, Reed et al2 first linked a drug to the onset of the disease, namely, hydrochlorothiazide. During almost 3 decades since that publication, multiple drugs have been linked to this phenomenon, now numbering more than 100 agents, and the occurrence of a drug as a cause or as an exacerbating agent represents roughly 20% of newly diagnosed cases of SCLE.3
Callen JP. Drug-Induced Subacute Cutaneous Lupus Erythematosus—Filling the Gap in Knowledge: Comment on “Subacute Cutaneous Lupus Erythematosus Induced by Chemotherapy”. JAMA Dermatol. 2013;149(9):1075–1076. doi:10.1001/jamadermatol.2013.4958
Browse and subscribe to JAMA Network podcasts!
Customize your JAMA Network experience by selecting one or more topics from the list below.
Create a personal account or sign in to: