[Skip to Navigation]
JAMA Dermatology a Century Ago
December 2013


JAMA Dermatol. 2013;149(12):1366. doi:10.1001/jamadermatol.2013.5877

On June 1, 1889, Charles-Édouard Brown-Séquard rocked his world. Starting with the premise that testes produced a dynamic substance that could retard aging and revive vitality, the esteemed Professor at the Collège de France described his autoinoculations with animal testicular extracts. The results were electrifying. Within days he was measurably stronger and noticeably more alert. Even his urine stream was more powerful! The medical community rushed to adopt Brown-Séquard’s organotherapy, and by the end of the year, 12 000 physicians were injecting Brown-Séquard's orchitic extract into their eager patients.

Add or change institution