The British scientist Charles Robert Darwin (1809-1882), famous for his contributions to the theory of evolution, was without question one of the most outstanding scientists in history. Only a few people know, however, that he also showed interest in the field of dermatology and described the anhidrotic ectodermal dysplasia as one of the first X-chromosomal, recessively inherited skin diseases.
In 1875, Charles Darwin reported in his work The Variation of Animals and Plants under Domestication1 a Hindu family that developed in the course of 4 generations “only four small and weak incisor teeth and […] eight posterior molars.”1