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February 1998

Erythematous Nodules in a Patient Infected With the Human Immunodeficiency Virus

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Arch Dermatol. 1998;134(2):231-236. doi:

The skin biopsy specimen demonstrated nodular aggregations of proliferated vessels with leukocytoclastic vasculitis changes surrounded by fibroplasia. Special stains (Warthin-Starry, periodic acid–Schiff, and acid-fast bacilli) were negative for microorganisms.

Erythema elevatum diutinum is a rare condition that is characterized by a chronic fibrosing leukocytoclastic vasculitis.1 It can occur at any age but tends to occur more frequently in middle-aged and older adults.2 It appears to have an equal sex ratio.

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