We appreciate the reply by Lebbé and Agbalika1 to our remarks on the role of human herpesvirus 8 in Kaposi sarcoma.2 However, they raise a point that might lead the lay reader to confound 2 main issues in virology, namely, latency and replication.
Drago F, Rebora A. Distinguishing the States of Latency and Reactivation Is Important for Human Herpesvirus 8. Arch Dermatol. 1998;134(5):633. doi:https://doi.org/
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