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Off-Center Fold
May 1998

Solitary Congenital Nodule in an Infant

Author Affiliations


Arch Dermatol. 1998;134(5):625-630. doi:

Hematoxylin-eosin–stained sections revealed central epidermal thinning with an overlying serous crust. Within the dermis, there was a dense infiltrate of histiocytic cells admixed with numerous eosinophils and a few scattered lymphocytes. The histiocytes had large round or reniform, vesicular, pale-staining nuclei with prominent nucleoli and abundant eosinophilic ground glass cytoplasm. Focal extravasation of red blood cells were seen in the papillary dermis. No mitotic figures or epidermotropism was noted.