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June 1998

Further Evidence That Syringolymphoid Hyperplasia With Alopecia Is a Cutaneous T-Cell Lymphoma

Arch Dermatol. 1998;134(6):753-754. doi:

Syringolymphoid hyperplasia with alopecia (SLHA) is a rare disease, which was first reported by Sarkany in 1969.1 Clinical features of SLHA include hairless patches with follicular papules. Histopathologic characteristics include a dense lymphohistiocytic infiltrate surrounding hyperplastic eccrine sweat glands and ducts. We report the ninth case of SLHA. Genotypical analysis revealed a biallelic monoclonal rearrangement of the T-cell receptor γ chain gene. This rearrangement provides further evidence that SLHA represents a cutaneous T-cell lymphoma.