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October 1998

Evaluation of Psoralen–UV-B (311-nm) Bath Phototoxicity

Arch Dermatol. 1998;134(10):1299-1300. doi:

Comparison of conventional psoralen–UV-A (PUVA) bath therapy with 311 nm of UV-B light after a bath with 0.15% solution of methoxsalen revealed the therapeutic efficacy of the narrow-band UV-B (311-nm) light in combination with methoxsalen bath (psoralen–UV-B [PUVB]) therapy in patients with psoriasis.1,2 However, no standardized guidelines exist for PUVB bath therapy. Therefore, the aim of our study was to determine the optimal time between methoxsalen bath treatment and UV-B irradiation, as well as the persistence of photosensitivity in healthy skin after PUVB bath treatment.