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December 1998

Lack of Association Between Aphthous Ulcers and Helicobacter pylori

Arch Dermatol. 1998;134(12):1634-1635. doi:

Aphthous ulcers are common, recurrent, painful, shallow ulcerations of the oral mucosa that usually resolve in 5 to 14 days. Studies have failed to find the precise etiologic factor.

Helicobacter pylori is a gram-negative coccobacillus responsible for 70% of gastric and 90% of duodenal ulcerations and has also been found in the dental plaque of patients with H pylori–related ulcers.1 These findings suggest that H pylori might also be the etiologic agent in aphthous ulcers.

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