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March 2000

Human Immunodeficiency Virus Infection and Cutaneous Aspergillosis

Author Affiliations

Copyright 2000 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.2000

Arch Dermatol. 2000;136(3):412-414. doi:10.1001/archderm.136.3.412

ASPERGILLOSIS CAN present as either an invasive or cutaneous infection. In the first instance, 1 or multiple organs are invaded, and hemorrhagic infarcts are very likely to develop. This occurs particularly when the patient is profoundly neutropenic due to underlying disease or therapy. In the latter instance, aspergillosis is apparent in the skin and can present (1) as primary cutaneous aspergillosis (PCA) derived from direct external inoculation through contact with objects such as armboards, external catheter sites, or surgical or other traumas; or (2) as secondary cutaneous aspergillosis caused by dissemination of the invasive disease to the skin.

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