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March 2000

Intralesional Interferon Treatment of Lentigo Maligna

Arch Dermatol. 2000;136(3):428-430. doi:

Lentigo maligna (LM) is considered a disordered proliferation of atypical melanocytes that grows slowly on sun-damaged skin of older people; 5% to 30% of cases progress to invasive melanoma.1 Lentigo maligna is managed with surgical therapy and wide excisions are often necessary, producing anesthetical and functional problems. Alternative therapies are Mohs micrographic surgery, cryosurgery, radiotherapy, and other treatments.1