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June 2000

Candida parapsilosis Chondritis Successfully Treated With Oral Fluconazole

Arch Dermatol. 2000;136(6):804. doi:

Candida parapsilosis infection can occur in any surgical setting. We present, to our knowledge, the first case of auricular C parapsilosis chondritis following Mohs micrographic surgery that was successfully treated with an oral antifungal agent (fluconazole).

A basal cell carcinoma of the ear was removed from a 65-year-old man by Mohs micrographic surgery, sparing the perichondrium. Repair was performed with a split-thickness skin graft that was viable 1 week after surgery. The grafted area developed tenderness and erythema 10 days postoperatively while the patient was taking cephalexin. On the 14th postoperative day, the cartilage became exposed and dry, with erythema and edema of the surrounding skin. There were no systemic signs and symptoms. Fenestration of the cartilage with a 3-mm punch biopsy allowed both histopathologic analysis and the establishment of a vascular base for wound granulation.