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July 2000

A Long-standing Dermal Nodule on the Neck of a Young Woman

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Copyright 2000 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.2000

Arch Dermatol. 2000;136(7):925-930. doi:

Microscopic examination of the excised tissue revealed mucinous glands with a draining duct, lined by ciliated pseudostratified columnar epithelium. Goblet cells were interspersed within the duct epithelium. There was no evidence of smooth muscle, cartilage, or thyroid tissue in the biopsy specimen. No inflammatory infiltrate or lymphoid follicles were observed.

Cutaneous bronchogenic cyst is a rare, benign congenital abnormality of embryonic foregut differentiation. More than 50 cases have been reported in the English-language literature.1,2 Most lesions are noted in infancy or childhood, and present as an asymptomatic swelling or draining sinus.3,4 The majority of lesions are located near the suprasternal notch or manubrium sterni. Less common sites include the neck, chin, and scapular region.4 The cysts predominantly affect males over females, with a ratio of 4:1.5 Histologically, bronchogenic cysts are lined by respiratory epithelium, which contains pseudostratified ciliated columnar cells. Smooth muscle, seromucinous glands, and cartilage are present in 80%, 50%, and 7% of these lesions, respectively.4

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