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August 2000

Recurrent Pustular Rash in a Pregnant Woman

Arch Dermatol. 2000;136(8):1055-1060. doi:

A 21-year-old gravida 2, para 1, white woman was referred at 26 weeks' gestation for evaluation of a painful generalized papulopustular eruption associated with weakness and malaise. Individual pustules on an erythematous base developed within the first month of gestation, with subsequent worsening and dissemination of the condition. During her first pregnancy, 18 months earlier, she had had a similar painful pustular eruption, although it was less severe and was confined to the third trimester. After an uncomplicated delivery, there was immediate clearing, with occasional outbreaks of papulopustules perimenstrually. There was no family history of dermatologic disease.