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JAMA Dermatology Clinicopathological Challenge
February 2015

Subareolar Nodule With Calcifications on Screening Mammography

Author Affiliations
  • 1Geisel School of Medicine at Dartmouth, West Lebanon, New Hampshire
JAMA Dermatol. 2015;151(2):227-228. doi:10.1001/jamadermatol.2014.2709

A healthy 60-year-old woman presented with a painless subareolar nodule of her left nipple measuring 2 cm in diameter (Figure, A) that had been present for several months. Screening mammography (Figure, B) performed 4 weeks prior revealed a large grouping of left breast subareolar calcifications extending into the skin and nipple. Follow-up ultrasonography demonstrated no discrete abnormal mass or shadowing but did show multiple echogenic foci consistent with findings on mammography. An incisional biopsy specimen of the mass was obtained and sent for histopathologic evaluation (Figure, C).