Are there differences in effectiveness between topical anti-inflammatory treatments (steroids, calcineurin inhibitors, or lithium salts) and placebo or azoles in the treatment of seborrheic dermatitis of the face and scalp in adults?
The topical anti-inflammatory treatments were more effective in achieving total clearance of symptoms than placebo by 1.4-fold to 8.5-fold, but there are no considerable differences in the anti-inflammatory topical treatments or in comparison with azoles for short-term treatment. There is no evidence of treatment effects in long-term, continuous, or intermittent use of these compounds despite the chronic nature of the disease.
Helena Kastarinen, Enembe O. Okokon, Jos H. Verbeek. Topical Anti-inflammatory Agents for Seborrheic Dermatitis of the Face or ScalpSummary of a Cochrane Review. JAMA Dermatol. 2015;151(2):221–222. doi:10.1001/jamadermatol.2014.3186
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