The present case highlights the nosologic complexity of monoclonal gammopathy (MG) associated with monotypic plasma cellular infiltrates in the absence of specific clinical skin lesions or systemic involvement.
An 85-year-old woman presented for basal cell carcinoma (BCC) reexcision from her right leg. She had a history of MG since 1996, with 6% plasma cells in her bone marrow at that time. No skin lesions clinically suggestive of plasmacytoma or cutaneous involvement by multiple myeloma (MM) or evidence of end-organ failure (ie, anemia, hypercalcemia, or renal insufficiency) were seen at any time.