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JAMA Dermatology Clinicopathological Challenge
October 2015

Pruritic, Pink Scaling Plaques on the Face and Trunk

Author Affiliations
  • 1Department of Dermatology, Drexel University College of Medicine, Philadelphia, Pennsylvania
  • 2Department of Medicine, Drexel University College of Medicine, Philadelphia, Pennsylvania
JAMA Dermatol. 2015;151(10):1123-1124. doi:10.1001/jamadermatol.2015.2103

A woman in her 40s with a medical history of pulmonary embolism and deep venous thrombosis presented with a 6-month history of pruritic, pink scaling plaques on her face and neck (Figure, A). The lesions subsequently involved her chest, abdomen, and back and flared with sun exposure. A diagnosis of lupus erythematosus (LE) was favored, but the lesions failed to improve on a regimen that included hydroxychloroquine sulfate, fluocinonide ointment, 0.05%, and tacrolimus ointment, 0.1%. Biopsy samples were obtained for histopathologic evaluation.