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JAMA Dermatology Clinicopathological Challenge
June 2016

Linear Vesicles in Newborn Resolving With Hyperpigmented Macules

Author Affiliations
  • 1Valencia University General Hospital Consortium, Valencia, Spain
JAMA Dermatol. 2016;152(6):711-712. doi:10.1001/jamadermatol.2016.0095

A 14-day-old girl presented with vesicular lesions over her trunk and lower extremities. According to her mother, lesions had started 2 days prior. Physical examination revealed vesicles filled with clear fluid disposed in a linear arrangement forming whorls and swirls (Figure, A).

Herpes simplex and varicella zoster virus polymerase chain reactions were negative. Syphilis, cytomegalovirus, and toxoplasma serologies were negative. Bacterial and fungal cultures of the vesicles were negative. A biopsy sample of a vesicle was obtained.